USP33

From Wikipedia, the free encyclopedia
Jump to: navigation, search
USP33
Protein USP33 PDB 2uzg.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases USP33, VDU1, ubiquitin specific peptidase 33
External IDs MGI: 2159711 HomoloGene: 8996 GeneCards: USP33
RNA expression pattern
PBB GE USP33 214843 s at fs.png

PBB GE USP33 212513 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015017
NM_201624
NM_201626

NM_001076676
NM_001252486
NM_133247

RefSeq (protein)

NP_055832
NP_963918
NP_963920

NP_001239415.1
NP_573510.2
NP_001070144
NP_001239415
NP_573510

Location (UCSC) Chr 1: 77.7 – 77.76 Mb Chr 3: 152.35 – 152.39 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 33 is an enzyme that in humans is encoded by the USP33 gene.[3][4]

Interactions[edit]

USP33 has been shown to interact with DIO2,[5] SELENBP1[6] and Von Hippel-Lindau tumor suppressor.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Puente XS, Sánchez LM, Overall CM, López-Otín C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–558. doi:10.1038/nrg1111. PMID 12838346. 
  4. ^ "Entrez Gene: USP33 ubiquitin specific peptidase 33". 
  5. ^ Curcio-Morelli C, Zavacki AM, Christofollete M, Gereben B, de Freitas BC, Harney JW, Li Z, Wu G, Bianco AC (Jul 2003). "Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation". J. Clin. Invest. 112 (2): 189–196. doi:10.1172/JCI18348. PMC 164294Freely accessible. PMID 12865408. 
  6. ^ Jeong JY, Wang Y, Sytkowski AJ (Feb 2009). "Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner". Biochem. Biophys. Res. Commun. 379 (2): 583–588. doi:10.1016/j.bbrc.2008.12.110. PMID 19118533. 
  7. ^ Li Z, Na X, Wang D, Schoen SR, Messing EM, Wu G (Feb 2002). "Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein". J. Biol. Chem. 277 (7): 4656–4662. doi:10.1074/jbc.M108269200. PMID 11739384. 

Further reading[edit]