USP6

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USP6
Identifiers
AliasesUSP6, HRP1, TRE17, TRE2, TRESMCR, Tre-2, USP6-short, ubiquitin specific peptidase 6
External IDsHomoloGene: 136783 GeneCards: USP6
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for USP6
Genomic location for USP6
Band17p13.2Start5,116,438 bp[1]
End5,175,034 bp[1]
RNA expression pattern
PBB GE USP6 206405 x at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001304284
NM_004505
NM_005152

n/a

RefSeq (protein)

NP_001291213
NP_004496

n/a

Location (UCSC)Chr 17: 5.12 – 5.18 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Ubiquitin carboxyl-terminal hydrolase 6 is an enzyme that in humans is encoded by the USP6 gene.[3][4][5]

Aneurysmal bone cyst can be associated with a TRE17/USP6 translocation.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000129204 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". 
  3. ^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. 
  4. ^ Hoogendijk JE, Hensels GW, Gabreels-Festen AA, Gabreels FJ, Janssen EA, de Jonghe P, Martin JJ, van Broeckhoven C, Valentijn LJ, Baas F, et al. (May 1992). "De-novo mutation in hereditary motor and sensory neuropathy type I". Lancet. 339 (8801): 1081–2. doi:10.1016/0140-6736(92)90668-S. PMID 1349106. 
  5. ^ "Entrez Gene: USP6 ubiquitin specific peptidase 6 (Tre-2 oncogene)". 
  6. ^ Ye Y, Pringle LM, Lau AW, et al. (June 2010). "TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NFκB". Oncogene. 29 (25): 3619–29. doi:10.1038/onc.2010.116. PMC 2892027Freely accessible. PMID 20418905. 

Further reading[edit]