USP6

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USP6
Identifiers
Aliases USP6, HRP1, TRE17, TRE2, TRESMCR, Tre-2, USP6-short, ubiquitin specific peptidase 6
External IDs HomoloGene: 136783 GeneCards: 9098
RNA expression pattern
PBB GE USP6 206405 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001304284
NM_004505
NM_005152

n/a

RefSeq (protein)

NP_001291213.1
NP_004496.2

n/a

Location (UCSC) Chr 17: 5.12 – 5.18 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Ubiquitin carboxyl-terminal hydrolase 6 is an enzyme that in humans is encoded by the USP6 gene.[1][2][3]

Aneurysmal bone cyst can be associated with a TRE17/USP6 translocation.[4]


References[edit]

  1. ^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. 
  2. ^ Hoogendijk JE, Hensels GW, Gabreels-Festen AA, Gabreels FJ, Janssen EA, de Jonghe P, Martin JJ, van Broeckhoven C, Valentijn LJ, Baas F, et al. (May 1992). "De-novo mutation in hereditary motor and sensory neuropathy type I". Lancet 339 (8801): 1081–2. doi:10.1016/0140-6736(92)90668-S. PMID 1349106. 
  3. ^ "Entrez Gene: USP6 ubiquitin specific peptidase 6 (Tre-2 oncogene)". 
  4. ^ Ye Y, Pringle LM, Lau AW, et al. (June 2010). "TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NFκB". Oncogene 29 (25): 3619–29. doi:10.1038/onc.2010.116. PMC 2892027. PMID 20418905. 

Further reading[edit]