The university occupies a 2,100-acre (8.5 km2) campus in the Warin Chamrap district of Ubon Ratchathani Province, approximately 15 kilometers south of Ubon Ratchathani city. It has around 13,000 students in 10 faculties and 1 College.
The university's former English name, Ubon Ratchathani University, was mandated by its former president Prakob Wirojanagud who disliked the officially approved Royal Institute romanisation system that is used by the government to render the name of the province and city as Ubon Ratchathani. Staff and students protested against this alternative spelling as confusing for foreigners at whom romanization is aimed. The university returned to using the romanization in early 2010.
The university has students from all over Thailand, but most of its students are from the Isan region and from the southeast of Isan in particular.