Ulrich K. Laemmli

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Ulrich K. Laemmli
NationalitySwitzerland
Known forSDS-PAGE
AwardsLouis-Jeantet Prize for Medicine (1996)
Marcel Benoist Prize (1988)
Scientific career
FieldsBiochemistry

Ulrich K. Laemmli is a Professor in the biochemistry and molecular biology departments at University of Geneva. He is known for the refinement of SDS-PAGE, a widely used method for separating proteins based on their electrophoretic mobility.[1] His paper describing the method is among the most cited scholarly journal articles of all time.[2][3][4] His current research involves studying the structural organization of nuclei and chromatin within the cell.[5]

Major scientific contributions[edit]

Although electrophoresis was used to separate proteins before Laemmli's work, he made significant improvements to the method. The term "Laemmli buffer" is often used to describe an SDS-containing buffer that is used to prepare (denature) samples for SDS-PAGE.[1][6]

Awards and honors[edit]

References[edit]

  1. ^ a b Laemmli UK (August 1970). "Cleavage of structural proteins during the assembly of the head of bacteriophage T4". Nature. 227 (5259): 680–685. doi:10.1038/227680a0. PMID 5432063.
  2. ^ "Bio Infobank Library-Kinetics". BioInfoBank Institute. Retrieved 9 January 2010.
  3. ^ Garfield, Eugene (1998). "THE USE OF JOURNAL IMPACT FACTORS AND CITATION ANALYSIS FOR EVALUATION OF SCIENCE". The Scientist. Retrieved 9 January 2010.
  4. ^ Garfield, Eugene (12 February 1990). "The most cited papers of all time" (PDF). Current Comments. 13 (7): 2–14. Retrieved 9 January 2010.
  5. ^ "PROFESSOR ULRICH K. LAEMMLI". Geneva, Switzerland: Département de biologie moléculaire - Université de Genève. 17 October 2008. Retrieved 7 January 2010.
  6. ^ "SDS-Polyacrylamide Gel Electrophoresis (SDS-PAGE)". Gainesville, FL: EnCor Biotechnology Inc. 2010. Retrieved 9 January 2010.
  7. ^ "The winners of the Louis-Jeantet Prize for medicine". Louis-Jeante Foundation. Retrieved 14 October 2009.
  8. ^ LEMPINEN, EDWARD W. (24 November 2006). "AAAS Members Elected as Fellows" (PDF). Science. AAAS. 314 (5803): 1256–60 [1258]. doi:10.1126/science.314.5803.1256. Retrieved 7 January 2009.
  9. ^ "2006 annual report" (PDF). AAAS. 2006. p. 22. Retrieved 7 January 2010.

External links[edit]