Unicornuate uterus

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Unicornuate uterus
A unicornuate uterus as seen on a hysterosalpingogram
SpecialtyGynaecology Edit this on Wikidata

A unicornuate uterus represents a uterine malformation where the uterus is formed from one only of the paired Müllerian ducts while the other Müllerian duct does not develop or only in a rudimentary fashion. The sometimes called hemi-uterus has a single horn linked to the ipsilateral fallopian tube that faces its ovary.[1]

Signs and symptoms[edit]

Four types of uterine malformations.

Women with the condition may be asymptomatic and unaware of having a unicornuate uterus; normal pregnancy may occur. In a review of the literature Reichman et al. analyzed the data on pregnancy outcome of 290 women with a unicornuate uterus. 175 women had conceived for a total of 468 pregnancies. They found that about 50% of patients delivered a live baby. The rates for ectopic pregnancy was 2.7%, for miscarriage 34%, and for preterm delivery 20%, while the intrauterine demise rate was 10%.[2] Thus patients with a unicornuate uterus are at a higher risk for pregnancy loss and obstetrical complications.


The uterus is normally formed during embryogenesis by the fusion of the two Müllerian ducts. If one of the ducts does not develop, only one Müllerian duct contributes to the uterine development. This uterus may or may not be connected to Müllerian structure on the opposite site if the Müllerian duct on that site undergoes some development. A unicornuate uterus has a single cervix and vagina. Associated defects may affect the renal system, and less common, the skeleton.[citation needed]

The condition is much less common than these other uterine malformations: arcuate uterus, septate uterus, and bicornuate uterus. While the uterus didelphys is estimated to occur in 1/3,000 women,[3] the unicornuate uterus appears to be even more infrequent with an estimated occurrence of about 1/4,000.[2]


A pelvic examination will typically reveal a single vagina and a single cervix. Investigations are usually prompted on the basis of reproductive problems.[citation needed]

Helpful techniques to investigate the uterine structure are transvaginal ultrasonography and sonohysterography, hysterosalpingography, MRI, and hysteroscopy. More recently 3-D ultrasonography has been advocated as an excellent non-invasive method to evaluate uterine malformations.[4]

Rudimentary horn[edit]

A unicornuate uterus may be associated with a rudimentary horn on the opposite site. This horn may be communicating with the uterus, and linked to the ispilateral tube. Occasionally a pregnancy may implant into such a horn setting up a dangerous situation as such pregnancy can lead to a potentially fatal uterine rupture. Surgical resection of the horn is indicated.[5]


Patients with a unicornuate uterus may need special attention during pregnancy as miscarriage, fetal demise, premature birth, and malpresentation are more common.[2] It is unproven that cerclage procedures are helpful. A pregnancy in a rudimentary horn cannot be saved and needs to be removed with the horn to prevent a potentially fatal rupture of the horn and uterus.[citation needed]

Although it is unclear whether interventions before conception or early in pregnancy such as resection of the rudimentary horn and prophylactic cervical cerclage decidedly improve obstetrical outcomes, current practice suggests that such interventions may be helpful.[citation needed]


  1. ^ Khati, Nadia J.; Frazier, Aletta A.; Brindle, Kathleen A. (2012). "The Unicornuate Uterus and Its Variants". Journal of Ultrasound in Medicine. 31 (2): 319–331. doi:10.7863/jum.2012.31.2.319. ISSN 1550-9613. PMID 22298877. S2CID 22851496.
  2. ^ a b c Reichman, David; Laufer, Marc R.; Robinson, Barrett K. (2009). "Pregnancy outcomes in unicornuate uteri: A review". Fertility and Sterility. 91 (5): 1886–94. doi:10.1016/j.fertnstert.2008.02.163. PMID 18439594.
  3. ^ Grimbizis, G. F.; Camus, M; Tarlatzis, BC; Bontis, JN; Devroey, P (2001). "Clinical implications of uterine malformations and hysteroscopic treatment results". Human Reproduction Update. 7 (2): 161–74. doi:10.1093/humupd/7.2.161. PMID 11284660.
  4. ^ Woelfer, B (2001). "Reproductive outcomes in women with congenital uterine anomalies detected by three-dimensional ultrasound screening". Obstetrics & Gynecology. 98 (6): 1099–103. doi:10.1016/S0029-7844(01)01599-X. PMID 11755560. S2CID 37650526.
  5. ^ Dhar, H (2008). "Rupture of non-communicating rudimentary uterine horn pregnancy". Journal of the College of Physicians and Surgeons. 18 (1): 53–4. PMID 18452672.

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