Incumbent Senator Nathaniel B. Dial was opposed in the Democratic primary by Coleman Livingston Blease and James F. Byrnes. On August 26, Blease and Byrnes emerged as the top vote getters in the first primary. Blease won the runoff election on September 9 and was elected to a six-year term in the Senate because there was no opposition to the Democratic candidate in the general election.
Jordan, Frank E. The Primary State: A History of the Democratic Party in South Carolina, 1876-1962. pp. 68–69.
"Report of the Secretary of State to the General Assembly of South Carolina. Part II." Reports of State Officers Boards and Committees to the General Assembly of the State of South Carolina. Volume I. Columbia, SC: 1925, p. 59.