Headquarters and Laboratory Complex in Silver Spring, Maryland
|Traded as||NASDAQ: UTHR
S&P 400 Component
|Headquarters||Silver Spring, Maryland, United States|
United Therapeutics is a biotechnology company. It is listed on the NASDAQ. Its headquarters are located in Silver Spring, Maryland, with additional facilities in Research Triangle Park, North Carolina and Chertsey, Surrey, UK.
United Therapeutics was founded in 1996 by Martine Rothblatt, an American lawyer, author, and entrepreneur. In 1994, Rothblatt's young daughter was diagnosed with a fatal orphan disease, pulmonary arterial hypertension (PAH). Rothblatt sold her telecom stock and started the $3 million PPH Cure Foundation to fund PAH research. By 2002 the FDA had approved United Therapeutics new drug Remodulin an alternative to GlaxoSmithKline's Flolan. In 2002 Remodulin was priced at $90,000 per year and within "a year annual sales were $50 million." By 2010 sales rose to $300 million.
By 2010 "United Therapeutics shares had increased 800% from 1999 when the company went public.
By October 2012, United Therapeutics had a market capitalization of US$3 billion. Rothblatt received a total compensation of $31,581,896 in 2014. According to the "annual collaborative report" from Equilar and The New York Times, Rothblatt ranked 24th in the list of "200 highest-paid CEOs of large publicly traded companies" and fourth in the list of biopharmaceutical executives with the highest total compensation.
On December 31, 2014, United Therapeutics announced a deal with DEKA, for the development of a potential technology breakthrough in the subcutaneous delivery of its Remodulin (treprostinil) injection to patients with pulmonary arterial hypertension (PAH) via a pre-filled semi-disposable pump system. According to Martine Rothblatt, “The new DEKA semi-disposable pump system will advance the convenience and delivery of subcutaneous Remodulin”. Rothblatt is a collaborator on inventions with DEKA's founder Dean Kamen.
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According to Forbes journalist Tim Worstall, a "lucrative secondary market" emerged by 2015 in the form of vouchers that "require the FDA to shorten its decision deadline to six months from the standard 10 months—potentially giving companies an extra four months’ worth of sales. The voucher doesn’t guarantee the FDA will approve the drug." In August 2015 United Therapeutics sold the United States Food and Drug Administration voucher they were awarded in March 2015 for Unituxin, the new treatment for high-risk neuroblastoma in pediatric patients, to AbbVie for $350 million. A federal agency, the U.S. National Cancer Institute in partnership with the Children’s Oncology Group, were the initial developers of Unituxin. In 2010 United Therapeutics were under contract with NCI to "conduct late-stage clinical testing, and to manufacture and market the drug."
- America's Best Small Companies: #12 United Therapeutics
- Yahoo! Finance: United Therapeutics Corporation (UTHR)
- Commit To Buy United Therapeutics At $105, Earn 9% Annualized Using Options, Forbes, September 25, 2014
- United Therapeutics Corp. "Locations." Accessed 2015-10-04.
- Moukheiber, Zina (1 July 2002). "Jeni's Oil". Forbes. Retrieved 19 November 2015.
- Herper, Matthew (April 22, 2010). "From Satellites To Pharmaceuticals". Forbes. Retrieved September 8, 2014.
- Robert Hackett (September 12, 2014). "Highest-paid female executive seeks immortality—digitally". Fortune. Retrieved November 22, 2014.
Martine Rothblatt, the founder of Sirius satellite radio and pharmaceutical company United Therapeutics, was the highest paid female executive in America last year with total earnings of $38 million.
- "Drug Approval Package: Remodulin (Treprostinil Sodium) Injection". FDA. 21 May 2002. Retrieved 19 November 2015.
- Nicole Gray (29 May 2015), "Biopharma execs have big presence among top-paid CEOs", BioPharma Dive, retrieved 19 November 2015
- "United Therapeutics - DEKA Ink Deal for Remodulin System". Zacks.com. January 2, 2015. Retrieved December 12, 2016.
- "United Therapeutics and DEKA Sign Agreement for New PAH Remodulin Delivery System". Pulmonary Hypertension News. January 2, 2015. Retrieved December 12, 2016.
- "United Therapeutics Signs Deal With DEKA For New Remodulin Delivery System". RTT News. December 31, 2014. Retrieved December 12, 2016.
- Worstall, Tim (20 October 2015). "The Economic Proof That The FDA's Drug Regulation Makes Us All Poorer". Forbes. Retrieved 19 November 2015.
- Loftus, Peter (1 November 2015). "Drug Makers Buy Pricey Vouchers to Speed Products to Market". Wall Street Journal. Retrieved 19 November 2015.
- "FDA approves first therapy for high-risk neuroblastoma". http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm437460.htm. External link in