UpToDate is a company under the Wolters Kluwer Health division of Wolters Kluwer. Its main product is a software system that is a point of care medical resource. It requires a subscription for access which is $495 USD per year as of 2014.
It includes a collection of medical and patient information, access to Lexi-comp drug monographs and drug-to-drug, drug-to-herb and herb-to-herb interactions information, and a number of medical calculators.
UpToDate is marketed as an evidence-based clinical resource, and claims to have been written by over 5,700 physician authors, editors and peer reviewers. It is available both via the Internet and offline on personal computers or mobile devices.
The company was launched in 1992 by Dr. Burton D. Rose along with Dr. Joseph Rush out of Dr. Rose's home. They started with nephrology and have since added over twenty other specialties, with more in development.