The song debuted on the UK Singles Chart on 14 February 2009 (Valentine's Day) at number 72, four weeks ahead of the release date of the single based purely on downloads. The single peaked at number 14, becoming the band's second single out of their recent six to fail to chart in the UK Top 10. However, it did become their 20th consecutive UK Top 20 single. In Ireland the song debuted on Thursday 26 February 2009 at number 29 based on downloads, a week before the official release. The single peaked at number 14.
The video for "Up All Night" was debuted on 27 January 2009, with Mark Owen on lead vocals. The video was directed by Daniel Wolfe. It features Take That performing at a street party in Croydon, with footage of them on a lorry.Gary Barlow does not appear in the second half of the music video because his pregnant wife went into labour whilst filming.