The Upcountry History Museum is a history museum in Greenville, South Carolina that displays the regional history of fifteen upstate South Carolina counties from the early 18th century to the present. Exhibits designed by Christopher Chadbourne and Associates emphasize technology rather than artifacts "to engage the senses, ignite the imagination and transport visitors back in time."
The museum is located on Greenville's Heritage Green with The Children's Museum, the Greenville County Art Museum, the satellite Museum & Gallery of Bob Jones University, the Greenville County Main Library, and the Greenville Little Theatre. The museum opened in September 2007. It is operated by Furman University.
In 2015, the Upcountry History Museum was named a Smithsonian affiliate. Its first Smithsonian exhibit was Searching for the Seventies: The DOCUMERICA Photography Project.