Uracil dehydrogenase (EC 18.104.22.168, uracil oxidase) is an enzyme with systematic name uracil:(acceptor) oxidoreductase. This enzyme catalyses the following chemical reaction
- uracil + acceptor barbiturate + reduced acceptor
Also oxidizes thymine. The enzyme acts on the hydrated derivative of the substrate.
- ^ Hayaishi O, Kornberg A (May 1952). "Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes". The Journal of Biological Chemistry. 197 (2): 717–32. PMID 12981104.