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Description miRBase is the searchable microRNA database, a central repository of published microRNA sequences and annotation.
Data types captured microRNA annotations
Organisms All
Research center University of Manchester
Laboratory Faculty of Life Sciences
Authors Ana Kozomara
Primary citation Kozomara & al. (2011)[1]
Release date 2011
Data format FASTA, GFF, EMBL
Website or via FTP
Download URL
Versioning yes
Data release frequency semi-annually
Version 17

The miRBase database is an archive of microRNA sequences.[1][2][3][4][5] As of September 2010 miRBase (release 16) contains over 15 ,000 microRNA loci and over 17, 000 distinct mature sequences, from 142 species.[1] The miRBase registry provides a centralised system for assigning new names to microRNA genes.[6]

miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003.[7]


  1. ^ a b c Kozomara A, Griffiths-Jones S (2010). "miRBase: integrating microRNA annotation and deep-sequencing data". Nucleic Acids Res 39 (Database issue): D152–7. doi:10.1093/nar/gkq1027. PMC 3013655. PMID 21037258. 
  2. ^ Griffiths-Jones S (2010). "miRBase: microRNA sequences and annotation". Curr Protoc Bioinformatics: Unit 12.9.1–10. doi:10.1002/0471250953.bi1209s29. PMID 20205188. 
  3. ^ Griffiths-Jones S, Saini HK, Van Dongen S et al. (2007). "miRBase: tools for microRNA genomics". Nucleic Acids Res 36 (Database issue): D154–8. doi:10.1093/nar/gkm952. PMC 2238936. PMID 17991681. 
  4. ^ Griffiths-Jones S (2006). "miRBase: the MicroRNA Sequence Database". Methods Mol Biol 342: 129–38. doi:10.1385/1-59745-123-1:129. PMID 16957372. 
  5. ^ Griffiths-Jones S, Grocock RJ, Van Dongen S et al. (2006). "miRBase: microRNA sequences, targets and gene nomenclature". Nucleic Acids Res 34 (Database issue): D140–4. doi:10.1093/nar/gkj112. PMC 1347474. PMID 16381832. 
  6. ^ Ambros V, Bartel B, Bartel DP et al. (2003). "A uniform system for microRNA annotation". RNA 9 (3): 277–9. PMC 1370393. PMID 12592000. 
  7. ^ Griffiths-Jones S (January 2004). "The microRNA Registry". Nucleic Acids Res. 32 (Database issue): D109–11. doi:10.1093/nar/gkh023. PMC 308757. PMID 14681370. 

External links[edit]

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