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VER-3323 structure.png
PubChem CID
Chemical and physical data
Formula C11H15BrN2
Molar mass 255.154 g/mol
3D model (JSmol)

VER-3323 is a drug which acts as a selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with moderate selectivity for 5-HT2C, but relatively low affinity for 5-HT2A. It has potent anorectic effects in animal studies.[1][2][3][4]

See also[edit]


  1. ^ Knight AR, Misra A, Quirk K, Benwell K, Revell D, Kennett G, Bickerdike M (August 2004). "Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors". Naunyn-Schmiedeberg's Archives of Pharmacology. 370 (2): 114–23. doi:10.1007/s00210-004-0951-4. PMID 15322733. 
  2. ^ Halford JC, Harrold JA, Lawton CL, Blundell JE (March 2005). "Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity". Current Drug Targets. 6 (2): 201–13. doi:10.2174/1389450053174550. PMID 15777190. 
  3. ^ Schuhler S, Clark A, Joseph W, Patel A, Lehnen K, Stratford E, Horan TL, Fone KC, Ebling FJ (May 2005). "Involvement of 5-HT receptors in the regulation of food intake in Siberian hamsters". Journal of Neuroendocrinology. 17 (5): 276–85. doi:10.1111/j.1365-2826.2005.01303.x. PMID 15869562. 
  4. ^ Song J, Hanniford D, Doucette C, Graham E, Poole MF, Ting A, Sherf B, Harrington J, Brunden K, Stricker-Krongrad A (December 2005). "Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes". ASSAY and Drug Development Technologies. 3 (6): 649–59. doi:10.1089/adt.2005.3.649. PMID 16438660.