VE (nerve agent)

From Wikipedia, the free encyclopedia
Skeletal formula of VE
Ball-and-stick model of VE
IUPAC name
(S)-(ethyl {[2-(diethylamino)ethyl]sulfanyl}(ethyl)phosphinate)
3D model (JSmol)
  • InChI=1S/C10H24NO2PS/c1-5-11(6-2)9-10-15-14(12,8-4)13-7-3/h5-10H2,1-4H3 checkY
  • InChI=1/C10H24NO2PS/c1-5-11(6-2)9-10-15-14(12,8-4)13-7-3/h5-10H2,1-4H3
Molar mass 253.34 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

VE (S-(diethylamino)ethyl O-ethyl ethylphosphonothioate) is a "V-series" nerve agent closely related to the better-known VX nerve agent. It was first reported in 1958 as a pesticide.[1]

Like most of the agents in the V-series (with the exception of VX), VE has not been extensively studied outside of military science.[citation needed]

It is commonly theorized that the so-called "second-generation" V series agents came from a cold war era Russian chemical weapons development program.[citation needed] They may have been developed sometime between 1950 and 1990. They have similar lethal dose levels to VX (between 10–50 mg) and have similar symptoms and method of action to other nerve agents that act on cholinesterase, and treatment remains the same, but the window for effectively treating second generation V series seizures is shorter.[citation needed] In addition to the standard seizures, some of the second generation V series agents are known to cause comas.


  1. ^ GB 797603, Ghosh Ranajit, "New basic esters of thiophosphonic acids and salts thereof"