VPS36

VPS36
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HTH, 2ZME, 3CUQ
Identifiers
Aliases	VPS36, C13orf9, EAP45, CGI-145, vacuolar protein sorting 36 homolog
External IDs	OMIM: 610903; MGI: 1917410; HomoloGene: 9374; GeneCards: VPS36; OMA:VPS36 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	52,450,634 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	22,710,859 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; mucosa of ileum; ; skin of hip; ; skin of thigh; ; pancreatic epithelial cell; ; pancreatic ductal cell; ; tibialis anterior muscle; ; endothelial cell; ; skin of abdomen; ; gingival epithelium;
	Top expressed in
	trigeminal ganglion; ; urothelium; ; transitional epithelium of urinary bladder; ; Paneth cell; ; hair follicle; ; ureter; ; medullary collecting duct; ; otic vesicle; ; endocardial cushion; ; spermatid;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphatidylinositol-3-phosphate binding; protein C-terminus binding; ubiquitin binding; protein binding; lipid binding;
Cellular component	cytoplasm; cytosol; late endosome; membrane; late endosome membrane; lysosome; extracellular exosome; nucleus; endosome; ESCRT II complex;
Biological process	regulation of transcription, DNA-templated; multivesicular body assembly; transcription, DNA-templated; endosomal transport; protein transport; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; macroautophagy; transport; endosome transport via multivesicular body sorting pathway;
	Sources:Amigo / QuickGO
Orthologs
	51028
	70160
	ENSG00000136100
	ENSMUSG00000031479
	Q86VN1
	Q91XD6
	NM_016075; NM_001282168; NM_001282169
	NM_027338; NM_001368379
	NP_001269097; NP_001269098; NP_057159
	NP_081614; NP_001355308
	Wikidata
View/Edit Human	View/Edit Mouse

Vacuolar protein-sorting-associated protein 36 is a protein that in humans is encoded by the VPS36 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136100 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031479 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kamura T, Burian D, Khalili H, Schmidt SL, Sato S, Liu WJ, Conrad MN, Conaway RC, Conaway JW, Shilatifard A (May 2001). "Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose". J Biol Chem. 276 (19): 16528–33. doi:10.1074/jbc.M010142200. PMID 11278625.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (May 2005). "Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain". J Biol Chem. 280 (20): 19600–6. doi:10.1074/jbc.M501510200. PMID 15755741.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)".

References

Further reading