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Protein VTI1B PDB 1gl2.png
Available structures
PDBOrtholog search: PDBe RCSB
AliasesVTI1B, VTI1, VTI1-LIKE, VTI1L, VTI2, v-SNARE, vti1-rp1, vesicle transport through interaction with t-SNAREs 1B
External IDsOMIM: 603207 MGI: 1855688 HomoloGene: 38178 GeneCards: VTI1B
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for VTI1B
Genomic location for VTI1B
Band14q24.1Start67,647,085 bp[1]
End67,674,820 bp[1]
RNA expression pattern
PBB GE VTI1B 209452 s at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 14: 67.65 – 67.67 MbChr 12: 79.16 – 79.17 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Vesicle transport through interaction with t-SNAREs homolog 1B is a protein that in humans is encoded by the VTI1B gene.[5][6][7]


VTI1B has been shown to interact with STX8.[8][9]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100568 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021124 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Li HC, Tahara H, Tsuyama N, Ide T (July 1998). "A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts". Biochem Biophys Res Commun. 247 (1): 70–4. doi:10.1006/bbrc.1998.8737. PMID 9636656.
  6. ^ Fischer von Mollard G, Stevens TH (February 1998). "A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways". J Biol Chem. 273 (5): 2624–30. doi:10.1074/jbc.273.5.2624. PMID 9446565.
  7. ^ "Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast)".
  8. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
  9. ^ Subramaniam VN, Loh E, Horstmann H, Habermann A, Xu Y, Coe J, Griffiths G, Hong W (March 2000). "Preferential association of syntaxin 8 with the early endosome". J. Cell Sci. 113 (6): 997–1008. PMID 10683148.

Further reading[edit]