Validamycin

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Validamycin
Validamycin.svg
Names
IUPAC name
(1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl β-D-glucopyranoside
Other names
Validamycin A; Valimon; Validacin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.120.044
Properties
C20H35NO13
Molar mass 497.49 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Validamycin is an antibiotic and fungicide produced by Streptomyces hygroscopicus. It is used as an inhibitor of trehalase.[1] It is used for the control of sheath blight of rice and damping-off of cucumbers.

References[edit]

  1. ^ Li, H.; Su, H.; Kim, S. B.; Chang, Y. K.; Hong, S. K.; Seo, Y. G.; Kim, C. J. (2011). "Enhanced production of trehalose in Escherichia coli by homologous expression of otsBA in the presence of the trehalase inhibitor, validamycin A, at high osmolarity". Journal of Bioscience and Bioengineering. 113 (2): 224–32. PMID 22036231. doi:10.1016/j.jbiosc.2011.09.018.