Vamsi Mootha

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Vamsi K Mootha
ResidenceBoston, Massachusetts
CitizenshipUnited States
Alma materStanford University
Harvard–MIT Division of Health Sciences and Technology
EmployerHoward Hughes Medical Institute
Massachusetts General Hospital
Harvard Medical School

Vamsi K Mootha is an American physician-scientist and computational biologist of Indian descent. He is an Investigator of the Howard Hughes Medical Institute, Professor of Systems Biology and Medicine at Harvard Medical School, and is based in the Department of Molecular Biology at Massachusetts General Hospital. He is also a Senior Associate Member of the Broad Institute.[1]

He and his research group have made fundamental major contributions to mitochondrial biology. His group characterized the mammalian mitochondrial proteome, identified numerous Mendelian mitochondrial disease genes, discovered the molecular identity of the mitochondrial calcium uniporter, and made the unexpected discovery that in animal models, low oxygen can prevent and alleviate mitochondrial disease. His team has also created computational tools that are widely used in genomics research today.

He is a 2004 recipient of the Macarthur Foundation "genius award". He received the 2008 Daland Prize from the American Philosophical Society and a 2014 Padma Shri Award from the Republic of India, one of the highest civilian awards given by the Indian government.[2][3][4][5] He was elected to the United States National Academy of Sciences in 2014. In 2016, he was awarded the King Faisal International Prize for Science [6]

Mootha graduated from Kelly High School in Beaumont, Texas. Mootha received his BS in Mathematical and Computational Science from Stanford University and his M.D. from Harvard University. He completed his internship and residency in internal medicine at Brigham and Women's Hospital in Boston, and then pursued postdoctoral training with Eric Lander at the Whitehead Institute/MIT Center for Genome Research.[7]