Vegetation (pathology)

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In medicine, a vegetation is an abnormal growth[1] named for its similarity to natural vegetation.

Vegetations are often associated with endocarditis.[2][3][4]

It can be made of fibrin[5] and platelets.[6]


Certain conditions are associated with specific vegetation patterns:

Condition Size Infective?
infective endocarditis related to Staphylococcus aureus generally large yes
rheumatic fever related to Streptococcus pyogenes typically small
Libman-Sacks endocarditis related to systemic lupus erythematosus small no (sterile)
nonbacterial thrombotic endocarditis (NBTE) small no (sterile)


  1. ^ "Vegetation" at Dorland's Medical Dictionary
  2. ^ Miyata E, Satoh S, Inokuchi K, et al. (September 2007). "Three fatal cases of rapidly progressive infective endocarditis caused by Staphylococcus aureus: one case with huge vegetation" (– Scholar search). Circ. J. 71 (9): 1488–91. doi:10.1253/circj.71.1488. PMID 17721034. [dead link]
  3. ^ Gotsman I, Meirovitz A, Meizlish N, Gotsman M, Lotan C, Gilon D (May 2007). "Clinical and echocardiographic predictors of morbidity and mortality in infective endocarditis: the significance of vegetation size". Isr. Med. Assoc. J. 9 (5): 365–9. PMID 17591374. 
  4. ^ "eMedicine/Stedman Medical Dictionary Lookup!". 
  5. ^ "Pathology Education: Cardiovascular". 
  6. ^ "eMedicine/Stedman Medical Dictionary Lookup!".