Ventral posterolateral nucleus

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Ventral posterolateral nucleus
Thalamic nuclei
Part ofVentral posterior nucleus
Latinnucleus ventralis posterolateralis thalami
NeuroLex IDbirnlex_737
Anatomical terms of neuroanatomy

The ventral posterolateral nucleus (VPL) is a nucleus of the thalamus. Together with the ventral posteromedial nucleus (VPM), ventral posterior inferior nucleus (VPI) and ventromedial posterior nucleus (VMpo), it constitutes the ventral posterior nucleus. There is uncertainty in the location of VMpo, as determined by spinothalamic tract (STT) terminations and staining for calcium-binding proteins, and several authorities do not consider its existence as being proved.[1]

The nucleus ventralis posterior lateralis pars oralis (VPLo) is a subdivision of the ventral posterolateral thalamus which has substantial projections to the motor cortex.[2]

Input and output[edit]

The VPL receives information from the neospinothalamic tract and the medial lemniscus of the posterior column-medial lemniscus pathway. It then projects this sensory information to Brodmann's Areas 3, 1 and 2 in the postcentral gyrus. Collectively, Brodmann areas 3, 1 and 2 make up the primary somatosensory cortex of the brain.

Additional images[edit]

See also[edit]


  1. ^ Willis et al The Journal of Pain 2002;3:79-94; Graziano and Jones, The Journal of Neuroscience 2004;24:248–256
  2. ^ Bornschlegl, M; Asanuma, H (1987-12-22). "Importance of the projection from the sensory to the motor cortex for recovery of motor function following partial thalamic lesion in the monkey". Brain Research. 437 (1): 121–30. doi:10.1016/0006-8993(87)91533-2. PMID 2827861. S2CID 22353965.