Vesicular glutamate transporter 1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
SLC17A7
Identifiers
Aliases SLC17A7, BNPI, VGLUT1, solute carrier family 17 member 7
External IDs MGI: 1920211 HomoloGene: 113454 GeneCards: 57030
RNA expression pattern
PBB GE SLC17A7 204229 at tn.png

PBB GE SLC17A7 204230 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020309

NM_182993

RefSeq (protein)

NP_064705.1

NP_892038.2

Location (UCSC) Chr 19: 49.43 – 49.44 Mb Chr 7: 45.16 – 45.18 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene.[3][4][5]

The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ni B, Du Y, Wu X, DeHoff BS, Rosteck PR Jr, Paul SM (Jul 1996). "Molecular cloning, expression, and chromosomal localization of a human brain-specific Na(+)-dependent inorganic phosphate cotransporter". J Neurochem. 66 (6): 2227–38. doi:10.1046/j.1471-4159.1996.66062227.x. PMID 8632143. 
  4. ^ Aihara Y, Mashima H, Onda H, Hisano S, Kasuya H, Hori T, Yamada S, Tomura H, Yamada Y, Inoue I, Kojima I, Takeda J (Jun 2000). "Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter". J Neurochem. 74 (6): 2622–5. doi:10.1046/j.1471-4159.2000.0742622.x. PMID 10820226. 
  5. ^ a b "Entrez Gene: SLC17A7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.