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Parsonnet grew up in Newark, New Jersey and attended Weequahic High School before enrolling at Cornell University. He left Cornell to join the U.S. Navy Reserve during World War II. In 1947 he finished his medical studies at New York University School of Medicine.
In 1955, Parsonnet joined his father's practice at Newark Beth Israel Medical Center, in Newark, New Jersey, which his grandfathers, Max Danzis and Victor Parsonnet, founded in 1901. Parsonnet conducted research and studies with pioneers of the heart surgery field, Michael DeBakey and Denton Cooley (the first person in the United States to perform a heart transplant in 1968). Parsonnet was the first surgeon in New Jersey to implant a permanent pacemaker (1961) and to complete a heart transplant (1985) and kidney transplant. When asked about his success, he simply says, "I was in the right place at the right time." Dr. Parsonnet has been on the editorial boards of numerous academic publications, including an editor of The Medical Roundtable, Cardiovascular Edition, a peer-reviewed journal publishing expert roundtable discussions on compelling topics. The former chief of surgery at Newark Beth Israel Medical Center, is now the medical director of the Pacemaker and Defibrillator Evaluation Center and director of Surgical Research at Newark Beth Israel Medical Center. He helped co-found the North American Society of Pacing and Electrophysiology and is the author to over 600 articles and 5 books. He also holds five patents.
Parsonnet also has a deep love for music. Parsonnet grew up in a very musical family. His father was the chair for the New Jersey Symphony Orchestra (NJSO). In 1986, when his father died, Victor was asked to fill his spot. In 1991, Parsonnet became the chairman of the NJSO, a position which he held for 17 years. He is now the chairman emeritus for the NJSO.
- McGlone, Peggy. "Music from the Heart; Cardiac surgeon gives his life to Newark hospital, orchestra", New Jersey Jewish News, September 21, 2008. Accessed September 19, 2019. "Parsonnet was born in Newark on Aug. 29, 1924, the older of two children of Eugene and Rose Danzis Parsonnet. He attended Maple Avenue School and Weequahic High School before enrolling at Cornell University."
- Gialanella, Donna  "Victor Parsonnet - Music from the heart"], New Jersey Star Ledger, September 28, 2008, Accessed October 28, 2019. "He was the first in New Jersey to implant a permanent pacemaker, the first to perform an aortocoronary bypass and the first in the state to do a kidney and heart transplant."
- Bambarger, Charles "NJSO pays tribute to Victor Parsonnet", New Jersey Star Ledger, September 26, 2008. Accessed October 28, 2019. "Longtime board chairman Victor Parsonnet has stepped back as chairman emeritus."
- Parry, Wayne "'Seinfeld' Star Alexander, Southside Johnny In NJ Fame Hall", Associated Press, October 27, 2019. Access October 28, 2019. "Newark physician and professor Victor Parsonnet was also inducted. He's a cardiac surgeon who helped advance pacemaking."
"Victor Parsonnet MD, Professor Emeritus." Barnabas Health. Barnabas Health, n.d. Web. 1 Mar. 2014. <http://www.barnabashealth.org>.
Wiener, Robert. "A Surgeon’s Heart Beats to Music and Medicine." New Jersey Jewish News. New Jersey Jewish News, 2011. Web. 1 Mar. 2014. <http://www.njjewishnews.com/njjn.com/040308/njASurgeonsHeart.html>.