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Villa Borghese may refer to:
- The Villa Borghese Pinciana ("Borghese villa on the Pincian Hill"), the villa built by the architect Flaminio Ponzio (and, after his death, finished by his assistant Giovanni Vasanzio), developing sketches by Scipione Borghese, who used it as a villa suburbana, a party villa, at the edge of Rome, and to house his art collection.
- Any other villas held by the Borghese family
- Villa Borghese (film) a 1953 Italian film directed by Vittorio de Sica
- A 3D reconstruction of the decorated facades on the Louvre's web site