Vojtěch Šafařík (26 October 1829 in Újvidék, Bács-Bodrog County, Vojvodina, Hungary (today Serbia) – 2 July 1902 in Prague, Bohemia) was a Slovak chemist, specializing in inorganic chemistry. He wrote many popular textbooks as well as making over 20,000 observations of variable stars. His wife and co-worker Paulína Šafaříková was interested in the history and popularization of astronomy. Šafařík's father, Pavel Jozef Šafárik, was a Slovak philologist and historian.
The crater Šafařík on the Moon is named after him, and so is the minor planet 8336 Šafařík (in conjunction with his wife).