WNK3

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WNK3
Identifiers
Aliases WNK3, PRKWNK lysine deficient protein kinase 3
External IDs MGI: 2652875 HomoloGene: 32493 GeneCards: WNK3
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001002838
NM_020922

NM_001271678
NM_001271679

RefSeq (protein)

NP_001002838
NP_065973

NP_001258607.1
NP_001258608.1
NP_001258607
NP_001258608

Location (UCSC) Chr X: 54.19 – 54.36 Mb Chr X: 151.2 – 151.32 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a protein that in humans is encoded by the WNK3 gene.[3]

Function[edit]

WNK3 is a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase 3 dependent pathway.[3]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.