WNT11

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WNT11
Identifiers
Aliases WNT11, HWnt family member 11
External IDs MGI: 101948 HomoloGene: 20970 GeneCards: WNT11
Gene location (Human)
Chromosome 11 (human)
Chr. Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for WNT11
Genomic location for WNT11
Band 11q13.5 Start 76,186,325 bp[1]
End 76,210,736 bp[1]
RNA expression pattern
PBB GE WNT11 206737 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004626

NM_001285792
NM_001285794
NM_001285795
NM_009519

RefSeq (protein)

NP_004617

NP_001272721
NP_001272723
NP_001272724
NP_033545

Location (UCSC) Chr 11: 76.19 – 76.21 Mb Chr 11: 98.84 – 98.86 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein Wnt-11 is a protein that in humans is encoded by the WNT11 gene.[5][6]

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney, and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000085741 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015957 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Lako M, Strachan T, Bullen P, Wilson DI, Robson SC, Lindsay S (Dec 1998). "Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung". Gene. 219 (1–2): 101–10. doi:10.1016/S0378-1119(98)00393-X. PMID 9757009. 
  6. ^ a b "Entrez Gene: WNT11 wingless-type MMTV integration site family, member 11". 

Further reading[edit]