WNT11

From Wikipedia, the free encyclopedia
Jump to: navigation, search
WNT11
Identifiers
Aliases WNT11, HWnt family member 11
External IDs MGI: 101948 HomoloGene: 20970 GeneCards: 7481
RNA expression pattern
PBB GE WNT11 206737 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004626

NM_001285792
NM_001285794
NM_001285795
NM_009519

RefSeq (protein)

NP_004617.2

NP_001272721.1
NP_033545.1

Location (UCSC) Chr 11: 76.19 – 76.21 Mb Chr 7: 98.84 – 98.86 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protein Wnt-11 is a protein that in humans is encoded by the WNT11 gene.[1][2]

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney, and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.[2]

References[edit]

  1. ^ Lako M, Strachan T, Bullen P, Wilson DI, Robson SC, Lindsay S (Dec 1998). "Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung". Gene 219 (1–2): 101–10. doi:10.1016/S0378-1119(98)00393-X. PMID 9757009. 
  2. ^ a b "Entrez Gene: WNT11 wingless-type MMTV integration site family, member 11". 

Further reading[edit]