|Use||Promote wakefulness and alertness|
Eugeroics (originally, "eugrégorique" or "eugregoric"), also known as wakefulness-promoting agents and wakefulness-promoting drugs, are a class of drugs that promote wakefulness and alertness. Eugeroics are used medically for the treatment of certain sleeping disorders, such as excessive daytime sleepiness and narcolepsy. Eugeroics generally have a very low addictive potential.
The prototypical eugeroic is modafinil; other drugs in the class include adrafinil and armodafinil. Modafinil and armodafinil have been found to act as selective, weak, atypical dopamine reuptake inhibitors. Adrafinil is a prodrug of modafinil and therefore has the same mechanism of action as modafinil.
- Milgram, Norton W.; Callahan, Heather; Siwak, Christina (2006). "Adrafinil: A Novel Vigilance Promoting Agent". CNS Drug Reviews. 5 (3): 193–212. ISSN 1080-563X. doi:10.1111/j.1527-3458.1999.tb00100.x.
- "Provigil: Prescribing information" (PDF). United States Food and Drug Administration. Cephalon, Inc. January 2015. Retrieved 16 August 2015.
- "Nuvigil: Prescribing information" (PDF). United States Food and Drug Administration. Cephalon, Inc. April 2015. Retrieved 16 August 2015.