Walter Boron

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Walter F. Boron
Born (1949-11-18)November 18, 1949
Elyria, Ohio, United States of America
Alma mater Saint Louis University, Washington University in St. Louis
Scientific career
Institutions Case Western Reserve University
Academic advisors Emile L. Boulpaep, Albert Roos

Walter F. Boron (born November 18, 1949)[1] is an American scientist and the 72nd president of the American Physiological Society (from 1999 to 2000).[2] He is currently secretary-general of the International Union of Physiological Sciences.[3] Additionally, Boron is co-editor, along with Emile L. Boulpaep, of the textbook Medical Physiology and former editor-in-chief of two leading physiology journals, Physiological Reviews and Physiology.


Boron is the David N. and Inez Myers/Antonio Scarpa Professor and chairman of the Department of Physiology and Biophysics at Case Western Reserve University.[4] From 1980-2007, he was a member of the faculty of Yale University.

Boron's lifelong research interest has been acid-base homeostasis. With his colleagues, he was the first to demonstrate cell-pH regulation,[5][6] discovered and cloned several bicarbonate transporters,[7][8] elucidated the sensing of molecular carbon dioxide and bicarbonate,[9][2] and introduced several experimental paradigms for studying cellular acid-base physiology.[10][2]

More recently, following the initial descriptions of a membrane that is impermeable to gases and a channel that is permeable to gases, Boron's group has extended its interest to understanding mechanisms of gas movement through aquaporins[11][12] and Rh proteins, and the physiological significance of this movement.


Boron obtained his undergraduate degree in chemistry at Saint Louis University in 1971. He studied medicine and physiology at Washington University in St. Louis, where he received his M.D. and Ph.D. degrees in 1977 under the mentorship of Albert Roos.[13][14] During this time, Boron also collaborated with Paul De Weer and John Russell. Boron joined Yale University as a postdoctoral fellow with Emile L. Boulpaep in 1978.


  • Medical Physiology Walter F. Boron. 1st Edition (2002) [1]
  • Medical Physiology Walter F. Boron, Emile L. Boulpaep. 2nd Edition (2008) [2]
  • Medical Physiology Walter F. Boron, Emile L. Boulpaep. 3rd Edition (2016) [3]


  1. ^ Walter Boron Curriculum Vitae
  2. ^ a b c "Walter F. Boron". Presidents. American Physiological Society. Retrieved 23 March 2015. 72nd APS President (1999-2000)
  3. ^ IUPS Council
  4. ^ Department of Physiology and Biophysics, Case Western Reserve University
  5. ^ Russell, John M.; Boron, Walter F. (1976). "Role of chloride transport in regulation of intracellular pH". Nature. 264 (5581): 73–4. doi:10.1038/264073a0. PMID 12472.
  6. ^ Thomas, RC (September 1984). "Experimental displacement of intracellular pH and the mechanism of its subsequent recovery". The Journal of Physiology. 354: 3P–22P. PMID 6434728.
  7. ^ Boron, WF (July 2001). "Sodium-coupled bicarbonate transporters". Journal of the Pancreas. 2 (4 Suppl): 176–81. PMID 11875256.
  8. ^ Aalkjaer, C; Boedtkjer, E; Choi, I; Lee, S (October 2014). "Cation-coupled bicarbonate transporters". Comprehensive Physiology. 4 (4): 1605–37. doi:10.1002/cphy.c130005. PMC 4768804. PMID 25428855.
  9. ^ Boron, Walter F.; De Weer, Paul (1976). "Active proton transport stimulated by CO2/HCO3−, blocked by cyanide". Nature. 259 (5540): 240–1. doi:10.1038/259240a0. PMID 2874.
  10. ^ Boron, Walter F. (2006). "Acid-Base Transport by the Renal Proximal Tubule". Journal of the American Society of Nephrology. 17 (9): 2368–82. doi:10.1681/ASN.2006060620. PMID 16914536.
  11. ^ Musa-Aziz, Raif; Chen, Li-Ming; Pelletier, Marc F.; Boron, Walter F. (2009). "Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG". Proceedings of the National Academy of Sciences. 106 (13): 5406–11. doi:10.1073/pnas.0813231106. PMC 2664022. PMID 19273840.
  12. ^ Endeward, V; Arias-Hidalgo, M; Al-Samir, S; Gros, G (24 October 2017). "CO₂ Permeability of Biological Membranes and Role of CO₂ Channels". Membranes. 7 (4). doi:10.3390/membranes7040061. PMID 29064458.
  13. ^ The American Physiological Society
  14. ^ University, Wayne State. "Walter F. Boron M.D., Ph.D. - Physiology - Wayne State University". Retrieved 2018-03-31.

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