Wellcome Centre for Human Genetics
|Parent institution||University of Oxford|
|Key people||Yvonne Jones (deputy director)|
|Formerly called||Wellcome Trust Center for Human Genetics|
Henry Wellcome Building of Genomic Medicine, Oxford
The Wellcome Centre for Human Genetics is a human genetics research centre of the Nuffield Department of Medicine in the Medical Sciences Division, University of Oxford, funded by the Wellcome Trust among others.
Facilities & rescources
Within the WHG a number of 'cores' provide services to the researchers:
Oxford Genomics Centre
The Oxford Genomics Centre provides high throughput sequencing services, using Illumina HiSeq4000 2500 and NextSeq500 and MiSeq. They also offer Oxford Nanopore MinION and PromethION sequencing. There are also Array platforms for genotyping, gene expresison, and methylation including Illuminia Infinium, Affymetrix and Fluidigm.
Research Computing Core
The Research Computing Core provides access to computer resources including 4120 cores and 4.2 PB of storage.
The Transgenics Core provides access to genetically modified mice and cell lines.
Cellular Imaging Core provides microscopy facilities including fluorescence microscopy (including Fluorescence Correlation Spectroscopy (FCS), Fluorescence Lifetime Correlation Spectroscopy (FLCS), Fluorescence Lifetime Imaging Microscopy (FLIM), Total Internal Reflection Fluorescence Microscopy (TIRF), Photoactivated Localisation Microscopy (PALM), Spectral Imaging (SI) and Single Particle Tracking (SPT).
Statistical and population genetics
The WHG has been involved in many international statistical genetics advances including the Wellcome Trust Case Control Consortia (WTCCC, WTCCC2), the 1000 Genomes Project and the International HapMap Project.
Besides the director and deputy director, other key people involved in the WTCHG include Chris Holmes, Gilean McVean, Anthony Monaco, Richard Mott, David Ian Stuart and Hugh Christian Watkins.
- "Welcome to the WHG". well.ox.ac.uk. Retrieved 21 November 2018.
- Farrar, Steve (2000). "Vanguard digs deep into data at Oxford". Times Higher Education. Retrieved 19 December 2011.[dead link]
- Ramagopalan, S. V. (2008). "Life on top—working@ the Wellcome Trust Centre for Human Genetics: Scotland Yard for DNA detectives". New Biotechnology. 25 (1): 39–45. doi:10.1016/j.nbt.2008.04.007. PMID 18504015.
- "Sequencing - Oxford Genomics Centre". Oxford Genomics Centre. Retrieved 2017-12-01.
- "Arrays - Oxford Genomics Centre". Oxford Genomics Centre. Retrieved 2017-12-01.
- DDN Storage (2016-11-02), Making high-performance compute appropriate to population-scale biomedical data, retrieved 2017-12-01
- "Transgenics Core". Retrieved 2017-12-01.
- "Cellular Imaging - Wellcome Trust Centre for Human Genetics". www.well.ox.ac.uk. Retrieved 2017-12-01.
- "Research areas - Wellcome Trust Centre for Human Genetics". www.well.ox.ac.uk. Retrieved 2017-12-01.
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