After he entered high school, Wes decided that he wanted to devote all of his time to American football. He stopped playing all sports with the exception of football and spent his time training to be a champion. After graduation, Shivers attended a junior college prior to attending Mississippi State University. Shivers played on the football team as an offensive tackle. He was named a Junior College All-American, as well as being on the All-Southeastern Conference team. Shivers was drafted by the Tennessee Titans in the 7th round of the 2000 draft and played three games before being cut. Shivers became a police officer after retiring but retired from that to pursue MMA.
In his first career fight, Deuce McCallister broke his nose prior to the 1997 Egg Bowl. After picking up 4 stoppage wins in local Mississippi organizations, Shivers spent a good part of 2009 participating in the UFC's The Ultimate Fighter: Heavyweights. In his first fight, he lost a controversial majority decision to eventual semi-finalist James McSweeney.
After more than a year, Shivers returned to action, defeating Goldman Butler at Strikeforce Challengers: Wilcox vs. Ribeiro via KO.