Wesco was first named Wilson's Mills, after James Wilson, the proprietor of a local mill. A post office called Wilsons Mills was established in 1877, and the name was changed to Wesco in 1907. The present name is a contraction of the Western Electric Supply Company, a telephone utility.
- U.S. Geological Survey Geographic Names Information System: Wesco, Missouri
- Missouri Atlas & Gazetteer, DeLorme, 1998, First edition, p. 47 ISBN 0-89933-224-2
- "Crawford County Place Names, 1928–1945 (archived)". The State Historical Society of Missouri. Retrieved 25 September 2016.
- "Post Offices". Jim Forte Postal History. Retrieved 25 September 2016.
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