Wikipedia:WikiProject Cell Signaling

From Wikipedia, the free encyclopedia
Jump to: navigation, search

This MCB project subpage is no longer in use and is kept as a historical archive. Please go to the MCB project homepage or talk page for currently active sections.

Key components of the MAPK/ERK pathway, by JWSchmidt.

In 2007, some Wikipedians formed a project to better organize information in articles related to Cell Signaling and to help focus the efforts of other Wikipedians. This page and its subpages contain their suggestions up until 2013, when the project became inactive; If you would like to help, please inquire on the talk page and see the to-do list there.

For more information on WikiProjects, please see Wikipedia:WikiProject and Wikipedia:WikiProject/Best practices.


WikiProject on Cell Signaling


This project was dedicated to improving and organising the Wikipedia articles on cell signaling to provide a convenient and reliable reference of the known signal transduction pathways. It covers the pathway pages and individual protein pages related to them.

WikiProject Cell signaling assessment statistics worklistlogcategory


  • Creating comprehensive articles for each known cell signaling pathway
  • Organising cell signaling articles with navigation boxes like these: Wikipedia:WikiProject Molecular and Cellular Biology#Protein topics navigation boxes.
  • Organising and creating articles on notable proteins involved in signaling pathways.
  • Providing each pathway with a clear diagram of its structure.
  • Clearly citing sources, especially for active research topics

Target audience[edit]

  • Introduction to pathway articles should make minimal use of jargon and be kept relatively simple
  • Subsections and protein pages can be more technical


This is a daughter project of WikiProject Molecular and Cellular Biology

Similar WikiProjects[edit]

WikiProject Clinical medicine and WikiProject Drugs may be relevant to this project.


Open Tasks[edit]

edit·history·watch·refresh Stock post message.svg To-do list for Wikipedia:WikiProject Cell Signaling:

Here are some tasks awaiting attention:



If you'd like to join the project, please add your name here. If you'd really like to contribute, but don't have much time, you can still participate by adding your name to the Guestlist.

Name Talk page Status Special interests
Rrten00 Talk EGFR,ErbB2, and MAPK, along with some knowledge of AKT and p53/p21
George Damoulakis Talk Casually active Small G proteins, PI 3-kinase signalling, immunology and neutrophil biology
Peter Znamenskiy Talk Cell culture and adult stem cells
F Guesdon Talk Casually active Molecular evolution in the Innate Immune system, particularly TLRs (Toll-like Receptor) and TAK1 (MAP3K7)
Rockpocket Talk G-protein coupled receptors
David Iberri Talk Embryogenesis (especially nervous system development)
John Schmidt Talk illustrations
Gacggt Talk Skeletal Muscle biology, Akt pathway, NF-kappaB pathway, some GPCRs, Neurotrophins, MuSK, agrin, Neuromuscular junction, etc.
Kohlasz Talk Chemotaxis
EquationDoc Talk Pathways involved in cancer prevention and formation Talk Immunology, development, endocrinology and reproductive physiology.
Biochemza Talk Casually active Immunology, neutrophils, tyrosine kinase signaling, calcium signaling
cyclopamine Talk Casually active Hedgehog pathway, Adult stem cells and cancer
Wisdom89 Talk Phospholipase, small and large G proteins
David.Throop Talk Working on Eicosanoid, Nonclassic eicosanoid and related articles. I am trying to get Eicosanoid up to FA status.
Jmcclare Talk Neurochemistry, G proteins, ion channels, pharmacology
Snellios Talk Casually active Knowledgeable on G proteins, ion channels, pharmacology (especially CNS pharmacology), calcium signaling.
ACGGGG Talk Casually active NF-kappaB, MAPKs, innate immunity
Stephen Helms Talk G proteins,phospholipase C,protein kinase C,calcium,scaffolding proteins,ion channels, and signaling organization
davebridges talk Casually active G proteins, GAPVD1, protein phosphorylation, pi3p
Subcellular talk Ion channels (particularly LGICs), calcium, GPCRs
JustAnotherKinase talk [Cell physiology, particularly in immunology and cardiovascular sciences.
Rod57 talk Casually active PI3K/AKT/mTOR pathway, Pathways involved in cancer prevention and formation
MChapman5 Talk Moderately active (for Spring 2013) Student in Graduate Level Signal Transduction Class; Undergraduate at Saint Louis University obtaining a B.S. in Biology.
Marcelo Behar Talk Casually active NF-kappaB,MAPKs,Yeast,Crosstalk_(biology), Regulation of signaling transduction, specificity/cross-talk control.


If you'd really like to contribute, but don't have much time, you can still participate by adding your name to the Guestlist.

Name Special interests

Tyciol (talk · contribs) Currently I'm studying biology but don't know enough about cell signaling to be an adequate participant, will once I study it in the future.
Jbarin (talk · contribs) Immunology, autoimmune disease, T cells, cytokines
Miguel AngeloR (talk · contribs) Im a student of Celular and Molecular Biology at the New University of Lisbon, I would like to contribute to this page seen as it is the main topic on my course. I so far have complete my Celular biology class in which most of this subject was discussed. I do not know much about how to contribute to wiki and work with other people on the same page, so if would like my help on any subject please contact me and informe about what i need to do. Tanks
Xarus Undergraduate student of Department of Biology in Yonsei Unv. Also working as an intern student in Glycomics lab. O-GlcNAc, Cell signaling
aqua112233 (talk · contribs) Immunology, cytokines
stevia_badger (talk · contribs) Undergraduate in Cell & Molecular Biology and Biochemistry departments. Decent access to primary literature for citations, through institutional libraries/databases. Currently working to get familiar with Wikipedia's editing format, so please let me know if there are any relatively simple tasks in need of completion for the project.

Article Structure[edit]

Proposed structure of a pathway article:

  • General introduction - keep it simple and clear
  • History/Discovery - discovery, seminal papers
  • Mechanism - the proteins involved and how they interact.
  • Role - the role of the pathway
  • Human disease - alternatively this can be incorporated into the previous section
  • Current research - recent advances, future directions

For individual proteins, see suggestions in Wikipedia:WikiProject_Molecular_and_Cellular_Biology#Structures

Proposed scheme for pathway diagrams is described here. Please do comment and contribute.

Hierarchy definition[edit]

No classification of this project has been defined.


Cell signaling and signal transduction is a very broad field. This section breaks this WikiProject down into smaller, more manageable "mini" projects, with a more specific subject set. Please feel free to add a mini project according to your expertise, or jump in and help on a specific mini project.

  • Tyrosine kinase signaling.

Adopt an article[edit]

Similar to the Collaboration of the week, but on a smaller scale, you might want to "adopt" an article. This would involve doing the research, writing, and picture-taking (if possible) for either a non-existent article or a stub. Of course, everyone else can still edit an adopted article, and you can work on other things too, but the idea is to find a focus for a while, to try and build up the number of quality articles the Project has produced.

General strategy and discussion forums[edit]



To do

WikiProject Banners[edit]

{{Template:Cell Signaling Project|class=???|importance=???}}

WikiProject Cell Signaling (Rated NA-class)
WikiProject icon
This page is part of WikiProject Cell Signaling, an attempt to better organise information in articles related to cell signaling and signal transduction. If you would like to participate, you can edit the article attached to this page, or visit the Cell Signaling WikiProject project, where you can join the project and/or contribute to the discussion.
 NA  This page does not require a rating on the project's quality scale.




Specific pathways[edit]


{{Template:TGF beta signaling}}

{{Template:Calcium signaling}}

{{Template:MAP kinase activation}}

Signaling molecules[edit]

{{Template:Signaling proteins}}


{{Template:Serine/threonine-specific protein kinases}}


{{Template:Tyrosine kinases}}

{{Template:Protein tyrosine phosphatases}}


- Is there a reason that these templates cannot be combined into one large template, so students can see what they are looking at specifically? For example, why not put the "Transmembrane Receptors" and "Cell Surface Receptors" Templates under the "Receptors" Template?

- Also why are there two "Cytokine Receptors" Templates here, and two "Transmembrane Receptors" templates here as well?

{{Template:Receptor agonists and antagonists}}

{{Template:T cell receptor}}

{{Template:Growth factor receptors}}

{{Template:Transmembrane receptors}}

{{Template:Tumor necrosis factor receptor superfamily}}

{{Template:Neuropeptide receptors}}

{{Template:G protein-coupled receptors}}

{{Template:Immune receptors}}

{{Template:Chemokine receptors}}

Other molecules[edit]

{{Template:Adaptor proteins}}


Articles in Categories[edit]

Discussion Archives[edit]


Wikifying Tools[edit]

(From Wikipedia:WikiProject_Wikify)

  • Can We Link It? - tool for suggesting and adding possible wiki links to articles. Progressively learns what's a good and a bad link. See here for more info. Also checks for unbalanced wiki syntax, which is sometimes a problem when articles are added by new users.
  • The Wikipedia Toolbar for the Firefox web-browser can make editing, formatting and linking much more efficient.
  • Also useful is the wikification toolbox containing quick links to Wiki guidelines and handy code snippets

Categorisation tools[edit]

(From Wikipedia:WikiProject Categories)

Sister Project links[edit]

External links[edit]