William Borough (1536–1599) was a British naval officer and the younger brother of Stephen Borough. He participated in the British attack on Cádiz in 1587. He was responsible for the drawing of several early maps including one of Russia.
Borough was born at Borough House, Northam Burrows, Northam, Devon and his childhood experiences of voyages were those accompanying his older brother Stephen Borough and their uncle John Borough. In 1580 Borough was appointed comptroller of the queen's ships, which post he shared initially with William Holstocke. In June 1583 he took ten pirate ships into custody and ensured that all ten masters were hanged at Wapping. In 1587 he sailed with Sir Francis Drake and was indicted for mutiny and cowardice but later acquitted and given command of the galley Bonavolia.