Sir William Butts (c. 1486 – 22 November 1545) was a member of King Henry VIII of England's court and served as the King's physician.
Butts died in 1545, and is buried at All Saints Church, Fulham, London.
Butts was a known Protestant and close associate of Thomas Cranmer, Archbishop of Canterbury, and Catherine Parr, the sixth wife of Henry VIII. His family later became significant leaders of the Puritan faction in Norfolk.
Butts had three children,
- Sir William Butts of Thornage, (c1506 - 1583) (m. Joan Bures). Butts was a patron of literature. After his death a collection of poems, A Book of Epitaphes (1583) was published in his memory. He is also the subject of a notable portrait by Holbein.
- Thomas Butts of Great Riburgh (m. Bridget Bures), who participated in the voyage of Richard Hore.
- Edmund Butts of Barrow (m. Anne Bures)
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- Venn, J. A., comp.. Alumni Cantabrigienses. London, England: Cambridge University Press, 1922-1954.
- Stephen, Sir Leslie, ed. Dictionary of National Biography, 1921–1922. Volumes 1–20, 22. London, England: Oxford University Press, 1921–1922.
- The Last Days of Henry VIII, Robert Hutchinson, p.135