With great power comes great responsibility
"With great power comes great responsibility" is a popular quote / phrase, motto and proverb that was originally made popular within Spider-Man comic books that debuted in Amazing Fantasy #15 written by Stan Lee. The quote is often used in politics, is commonly used among journalists and book authors and is used in popular culture such as in various media and memes.
In Spider-Man stories
The thematic and often-quoted (including by the Supreme Court of the United States) Spider-Man phrase with great power comes great responsibility is widely attributed to Uncle Ben. However, in Amazing Fantasy #15, where it first appears, it is not spoken by any character. In fact, Ben has only two lines in the entire comic. The original version of the phrase appears in a narrative caption of the comic's last panel, rather than as spoken dialogue. It reads, "...with great power there must also come -- great responsibility!".
However, later stories and flashbacks that took place when Ben was still alive retroactively made the phrase one of Ben's many homilies he would lecture Peter with. Latter-day reinterpretations of Spider-Man, such as the Spider-Man film and the Ultimate Spider-Man comic, depict Ben as saying this phrase to Peter while he is still alive, in their last conversation.
Origin and source
The origins of the phrase pre-date its use in Spider-Man, though its exact origins are unclear. In a "Plan de travail, de surveillance et de correspondance, proposé par le Comité de Salut Public aux Représentans du Peuple, députés prés des Armées de la République" of the French National Convention in 1793, , we can find a sentence about the representatives saying "ils doivent envisager qu'une grande responsabilité est la suite inséparable d'un grand pouvoir", which could translate by "they must contemplate that a great responsibility is inseparable from a great power." In 1817, British Member of Parliament William Lamb is recorded saying, "the possession of great power necessarily implies great responsibility." In 1906, Under-Secretary of the Colonial Office Winston Churchill said, "Where there is great power there is great responsibility", even indicating that it was already a cultural maxim invoked toward government at the time. 
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