The Wuhan Union Hospital (Chinese: 武汉协和医院; pinyin: Wǔhàn Xiéhé Yīyuàn) is a hospital in Jianghan District, Wuhan, Hubei, China.
The hospital was founded by Griffith John in 1866 as Hankow Renji Hospital. In 1928, it was renamed as Hankow Union Hospital. In 1950, it was placed under the jurisdiction of Medical College of Wuhan University. In 1953, it became the First Affiliated Hospital of Wuhan Medical College. In 1985, it became the Union Hospital of Tongji Medical University. In 2000, it became the Union Hospital of Tongji Medical College of Huazhong University of Science and Technology.
In 2020, the hospital became one of the designated hospital to treat patients from the 2019–20 coronavirus pandemic.
The hospital consists of the Main Campus, West Campus, Tumor Center and Jinyinhu Hospital. It can accommodate a total of 5,000 beds.
The hospital is accessible within walking distance east of Zhongshan Park Station of Wuhan Metro.