XII International AIDS Conference, 1998
The Journal of the American Medical Association (JAMA) devoted the July issue of their magazine to HIV topics to support the conference, and chose especially to focus on two studies which would be presented at the conference. One focus was Roy Gulick's study on combination therapy for reducing viral load in HIV positive persons, in which AZT, 3TC and indinavir were shown to cause study participants to lower their viral load to undetectable levels. The other was Michael Giordano's study which showed that HIV positive mothers could reduce the risk of transmission of HIV to their child by elective cesarean section, taking AZT before delivery of the child, and taking AZT intravenously during the delivery.
Price of drugs
The Gay Men's Health Crisis stated that drug marketing for Efavirenz was part of this conference and that over 100 organizations worldwide had come together to issue a "Fair Price Consensus Statement" to guide policymakers on regulating the pricing of drugs. The issue was that Efavirenz was slated to go to market costing an average of $5000 per year and its efficacy was not proven over existing treatments, and GMHC and others were calling for expert oversight, pricing at rates which average people could afford, and greater community involvement in HIV/AIDS issues in general.
Lancet editor Richard Horton stated his belief that the conference failed to facilitate discussion between the developed world and the developing world, and thus failed to keep to its advertised theme of "bridging the gap."
Roy M. Gulick, MD, MPH; John W. Mellors, MD; Diane Havlir et al., Simultaneous vs Sequential Initiation of Therapy With Indinavir, Zidovudine, and Lamivudine for HIV-1 Infection, JAMA, July 1, 1998—Vol 280, No. 1.
- Michael Giordano (2011). "Briefing on the Journal of the American Medical Association's HIV/AIDS Issue". thebody.com. Retrieved 18 April 2011.
- Grinberf, Linda. "What Price Efavirenz". GMHC Treatment Issues (Gay Men's Health Crisis) (September 1998). Retrieved 22 October 2011.
- Richard Horton (11 July 1998). "The 12th World AIDS Conference: a cautionary tale". The Lancet (Elsevier) 352 (9122): 122. doi:10.1016/S0140-6736(98)85034-4. Retrieved 17 April 2011.