XYLT1

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XYLT1
Identifiers
Aliases XYLT1, DBQD2, PXT-I, XT1, XTI, XYLTI, xylT-I, xylosyltransferase 1
External IDs MGI: 2451073 HomoloGene: 32534 GeneCards: XYLT1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022166

NM_175645

RefSeq (protein)

NP_071449

NP_783576.2
NP_783576

Location (UCSC) Chr 16: 17.1 – 17.47 Mb Chr 7: 117.38 – 117.67 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Xylosyltransferase 1 is an enzyme that in humans is encoded by the XYLT1 gene.[3][4]

Xylosyltransferase (XT; EC 2.4.2.26) catalyzes the transfer of UDP-xylose to serine residues within XT recognition sequences of target proteins. Addition of this xylose to the core protein is required for the biosynthesis of the glycosaminoglycan chains characteristic of proteoglycans.[supplied by OMIM][4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Gotting C, Kuhn J, Zahn R, Brinkmann T, Kleesiek K (Jan 2001). "Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II". J Mol Biol. 304 (4): 517–28. doi:10.1006/jmbi.2000.4261. PMID 11099377. 
  4. ^ a b "Entrez Gene: XYLT1 xylosyltransferase I". 

Further reading[edit]