Xanthelasma is a sharply demarcated yellowish deposit of cholesterol underneath the skin, usually on or around the eyelids. While they are neither harmful to the skin nor painful, these minor growths may be disfiguring and can be removed. There is no high-quality evidence that xanthelasma deposits are related to blood low-density lipoprotein levels or increased risk of atherosclerosis.
This section is empty. You can help by adding to it. (November 2017)
Recurrence is common: 40% of patients with XP had recurrence after primary surgical excision, 60% after secondary excision, and 80% when all four eyelids were involved. A possible cause might be insufficiently deep excisions. 
Xanthelasma is a rare disorder in the General population, with a variable incidence of 0.56%–1.5% in western developed countries. The age of onset ranges ranges from 15 to 75 with a peak in the 4th to 5th decades of life. There also seems to be a greater prevalance in females, but this might be due to higher consciousness to cosmetic defects
The word is derived from Greek xanthós, ξανθός , "yellow" and élasma, έλασμα, "foil". The plural is xanthelasmata.
- Xanthoma, which are similar collections of cholesterol around tendons
- List of xanthoma variants associated with hyperlipoproteinemia subtypes
- Frew JW, Murrell DF, Haber RM (October 2015). "Fifty shades of yellow: a review of the xanthodermatoses". International Journal of Dermatology. 54 (10): 1109–23. doi:10.1111/ijd.12945. PMID 26227781.
- Ozdöl S, Sahin S, Tokgözoğlu L (August 2008). "Xanthelasma palpebrarum and its relation to atherosclerotic risk factors and lipoprotein (a)". International Journal of Dermatology. 47 (8): 785–9. doi:10.1111/j.1365-4632.2008.03690.x. PMID 18717856.
- Shields C, Shields J (2008). Eyelid, conjunctival and orbital tumors: atlas and textbook. Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-7578-7.[page needed]
- Xanthelasma. Mosby's Medical Dictionary (8th ed.). 2009. Retrieved November 8, 2012.
- Nair PA, Singhal R (2017-12-18). "Xanthelasma palpebrarum - a brief review". Clinical, Cosmetic and Investigational Dermatology. 11: 1–5. doi:10.2147/CCID.S130116. PMC 5739544. PMID 29296091.
- Jain A, Goyal P, Nigam PK, Gurbaksh H, Sharma RC (September 2007). "Xanthelasma Palpebrarum-clinical and biochemical profile in a tertiary care hospital of Delhi". Indian Journal of Clinical Biochemistry. 22 (2): 151–3. doi:10.1007/BF02913335. PMC 3453794. PMID 23105704.