Y-27632

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Y-27632
Y-27632.svg
Names
IUPAC name
(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide
Identifiers
3D model (Jmol)
ChEBI
ChemSpider
DrugBank
Properties
C14H21N3O
Molar mass 247.34 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Y-27632 is a biochemical tool used in the study of the rho-associated protein kinase (ROCK) signaling pathways.[1] Y-27632 selectively inhibits p160ROCK.[2]

References[edit]

  1. ^ Uehata, Masayoshi (1999). "Y-27632. Selective probe of ROCK/Rho-kinase". Jikken Igaku. 17 (7): 850–855. 
  2. ^ Uehata, M; Ishizaki, T; Satoh, H; Ono, T; Kawahara, T; Morishita, T; Tamakawa, H; Yamagami, K; et al. (1997). "Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension". Nature. 389 (6654): 990–4. doi:10.1038/40187. PMID 9353125.