Yaakov Herzog was born in Dublin, Ireland. His father was Yitzhak HaLevi Herzog, the second Ashkenazi Chief Rabbi of Israel, and his brother, Chaim Herzog, became the sixth President of Israel. The family immigrated to Mandate Palestine in 1937. After he was ordained as a rabbi in the Harry Fischel Seminary in Jerusalem, Herzog studied law at the Hebrew University of Jerusalem and London University. He earned a doctorate in international law from McGill University in Montreal. Herzog served in Shai (Haganah unit) in the Haganah.
After the founding of the State of Israel, Herzog worked for the Israel Ministry of Foreign Affairs. From 1948 to 1954 he counseled on issues relating to Jerusalem. From 1954 to 1957 he was the chief of the United States division. He advised Prime Minister of Israel David Ben-Gurion on policy from 1956 to 1957.
Herzog helped improve relations with the Vatican after the Six-Day War, and led diplomatic communications with King Hussein of Jordan. He held secret talks with Hussein in a London clinic that opened the way to peace between Jordan and Israel, established secret contacts with Lebanese Christians, helped the Imam of Yemen against his enemies, and became a personal friend to President Kennedy, Secretary of State John Foster Dulles, Ireland’s leader Éamon de Valera and other world figures.
From 1965 until his death in 1972, he served as the director-general of the Prime Minister of Israel's office under the administrations of Levi Eshkol and Golda Meir. In January 1961, when he was ambassador in Canada, he engaged in a famous public debate with the British historian Arnold J. Toynbee, who called the Jewish people a "fossil" and compared Israel's actions in the 1948 Arab-Israeli War to the actions of the Nazis against the Jews in the Holocaust.
Isaiah Berlin described him as "one of the best and wisest, most attractive and morally most impressive human beings I have ever known.” Yehuda Avner called him "one of Israel's commanding intellects, possessed of a subtle and powerful mind, who was equally at home with Bach as he was with the Bible."
Many educational institutions, especially in the Religious Zionism sector, perpetuate his memory: Kiryat Yaakov Herzog high school in Kfar Saba, Yaakov Herzog Jewish Studies College in Ein Tzurim, Herzog College for training of teachers in Alon Shvut, the Maalot Yaakov Yeshiva, and the law faculty at Bar-Ilan University, are all named for him.
- A translation of Berakhot, Pe'ah and Demai was first printed in 1947 and reprinted in 1980.
- About Israel and its land: an argument with Professor Arnold Toynbee. Jerusalem: Office of Education and Culture, 5735 (1974-1975).
- A nation that lives alone. Tel Aviv: Maariv books, 1975.
- The Anderson Mission
- This is how we ruined Toynbee's theory
- Yaacov Herzog, A Biography: The Life and Times of a Jewish Prince
- Merkaz Herzog: Who was Yaacov Herzog
- Yehuda Avner, The Prime Ministers, p. 141
- Segments from Yaakov Herzog's argument with Arnold Toynbee (Hebrew)
- Short biography of Yaakov Herzog Yaakov Herzog Centre for Jewish Studies (Hebrew)