Yarumal

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Yarumal
Municipality and town
Centro Yarumal.JPG
Flag of Yarumal
Flag
Official seal of Yarumal
Seal
Location of the municipality and town of Yarumal in the Antioquia Department of Colombia
Location of the municipality and town of Yarumal in the Antioquia Department of Colombia
Yarumal is located in Colombia
Yarumal
Yarumal
Location in Colombia
Coordinates: 6°57′48″N 75°25′2″W / 6.96333°N 75.41722°W / 6.96333; -75.41722
Country  Colombia
Department Antioquia Department
Subregion Northern
Elevation 2,265 m (7,431 ft)
Population (30 June 2005)
 • Total 26,603
Time zone Colombia Standard Time (UTC-5)

Yarumal is a municipality in the Antioquia Department, Colombia. Yarumal was founded in 1787 as San Luis de Gongora. Municipal status was granted in 1821. The current name of Yarumal comes from a local plant belonging to the Moraceae family, known in botanical Latin as Cecropia peltata L. The municipality (3 parishes and 20 villages) has an area of 724 km², 35,315 inhabitants, and its average elevation is 2,265 m above sea level.

Health[edit]

An unusually large proportion of the inhabitants suffer from early-onset Alzheimer's disease, which is caused by a genetic mutation. The genetic mutation is thought to have come from a Spanish conquistador. Approximately 5,000 residents will develop early-onset Alzheimer's. Half of the affected residents were shown to have developed symptoms by their early 40s.[1][2]

See also[edit]

References[edit]

  1. ^ Lalli, Matthew A.; Cox, Hannah C.; Arcila, Mary L.; Cadavid, Liliana; Moreno, Sonia; Garcia, Gloria; Madrigal, Lucia; Reiman, Eric M.; Arcos-Burgos, Mauricio (2014-10-01). "Origin of the PSEN1 E280A mutation causing early-onset Alzheimer's disease". Alzheimer's & Dementia 10 (5 Suppl): S277–S283.e10. doi:10.1016/j.jalz.2013.09.005. ISSN 1552-5279. PMC 4019728. PMID 24239249. 
  2. ^ Reitz, Christiane (2015-03-01). "Genetic diagnosis and prognosis of Alzheimer's disease: challenges and opportunities". Expert Review of Molecular Diagnostics 15 (3): 339–348. doi:10.1586/14737159.2015.1002469. ISSN 1744-8352. PMID 25634383. 

Coordinates: 7°00′N 75°30′W / 7.000°N 75.500°W / 7.000; -75.500