The town of Yoshino is located in the northern portion of Yoshino District. Most of the area is mountainous, but the section along the Yoshino River is somewhat flatter and contains most of the town's roads, train tracks and houses.
For adherents of Shugendo, Yoshino is the traditional beginning of the Mount Ōmine pilgrimage trail, although nowadays many hikers begin and end their trek in the Dorogawa district of Tenkawa Village.
Mount Yoshino is famous for its many thousands of sakura trees. These flowering cherry trees were planted in four groves at different altitudes, in part so that the trees would be visible coming into bloom at different times in the spring. An account of Yoshino written in about 1714 explained that, on their climb to the top, travelers would be able to enjoy the lower 1,000 cherry trees at the base, the middle 1,000 on the way, the upper 1,000 toward the top, and the 1,000 in the precincts of the inner shrine at the top.