ZBED3

ZBED3
Identifiers
Aliases	ZBED3, zinc finger BED-type containing 3
External IDs	OMIM: 615250 MGI: 1919364 HomoloGene: 12442 GeneCards: ZBED3
Gene location (Human) Chr. Chromosome 5 (human) Band 5q13.3 Start 77,072,072 bp End 77,087,285 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 D1 Start 95,460,120 bp End 95,474,349 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte retinal pigment epithelium smooth muscle tissue left lobe of thyroid gland subcutaneous adipose tissue right lobe of thyroid gland parotid gland body of pancreas left uterine tube renal cortex Top expressed in secondary oocyte yolk sac proximal tubule ovary endocardial cushion abdominal wall aortic valve neural tube ascending aorta entorhinal cortex More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding metal ion binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm membrane cytosol Biological process positive regulation of canonical Wnt signaling pathway negative regulation of protein phosphorylation protein stabilization Wnt signaling pathway positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84327 72114 Ensembl ENSG00000132846 ENSMUSG00000041995 UniProt Q96IU2 Q9D0L1 RefSeq (mRNA) NM_032367 NM_001329564 NM_028106 NM_001302538 NM_001302539 RefSeq (protein) NP_001316493 NP_115743 NP_001289467 NP_001289468 NP_082382 Location (UCSC) Chr 5: 77.07 – 77.09 Mb Chr 13: 95.46 – 95.47 Mb PubMed search
Wikidata
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Zinc finger BED domain-containing protein 3 also known as axin-interacting protein is a protein in humans that is encoded by the ZBED3 gene.

Further reading

• Hayward A, Ghazal A, Andersson G, Andersson L, Jern P (2013). Robinson-Rechavi M (ed.). "ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions". PLOS ONE. 8 (3): e59940. Bibcode:2013PLoSO...859940H. doi:10.1371/journal.pone.0059940. PMC 3606216. PMID 23533661.
• de Miguel-Yanes JM, Shrader P, Pencina MJ, Fox CS, Manning AK, Grant RW, Dupuis J, Florez JC, D'Agostino RB, Cupples LA, Meigs JB (Jan 2011). "Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms" (PDF). Diabetes Care. 34 (1): 121–5. doi:10.2337/dc10-1265. PMC 3005447. PMID 20889853.
• Chen T, Li M, Ding Y, Zhang LS, Xi Y, Pan WJ, Tao DL, Wang JY, Li L (Mar 2009). "Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling". The Journal of Biological Chemistry. 284 (11): 6683–9. doi:10.1074/jbc.M807753200. PMC 2652294. PMID 19141611.
• Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, et al. (Jul 2010). "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis". Nature Genetics. 42 (7): 579–89. doi:10.1038/ng.609. PMC 3080658. PMID 20581827.