ZBTB17

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Zinc finger and BTB domain containing 17
Protein ZBTB17 PDB 2Q81.png
Rendering based on PDB 2Q81​.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ZBTB17 ; MIZ-1; ZNF151; ZNF60; pHZ-67
External IDs OMIM604084 MGI107410 HomoloGene2575 GeneCards: ZBTB17 Gene
RNA expression pattern
PBB GE ZBTB17 203602 s at tn.png
PBB GE ZBTB17 203601 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7709 22642
Ensembl ENSG00000116809 ENSMUSG00000006215
UniProt Q13105 Q60821
RefSeq (mRNA) NM_001242884 NM_009541
RefSeq (protein) NP_001229813 NP_033567
Location (UCSC) Chr 1:
15.94 – 15.98 Mb
Chr 4:
141.44 – 141.47 Mb
PubMed search [1] [2]

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.[1]

Interactions[edit]

ZBTB17 has been shown to interact with TOPBP1,[2] Host cell factor C1[3] and Myc.[4][5]

References[edit]

  1. ^ "Entrez Gene: ZBTB17 zinc finger and BTB domain containing 17". 
  2. ^ Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, Syvaoja J, Saluz HP, Haenel F, Eilers M (Sep 2002). "Negative regulation of the mammalian UV response by Myc through association with Miz-1". Molecular Cell 10 (3): 509–21. doi:10.1016/S1097-2765(02)00633-0. PMID 12408820. 
  3. ^ Piluso D, Bilan P, Capone JP (Nov 2002). "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of Biological Chemistry 277 (48): 46799–808. doi:10.1074/jbc.M206226200. PMID 12244100. 
  4. ^ Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M (Apr 2001). "Repression of p15INK4b expression by Myc through association with Miz-1". Nature Cell Biology 3 (4): 392–9. doi:10.1038/35070076. PMID 11283613. 
  5. ^ Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M (Sep 1997). "An alternative pathway for gene regulation by Myc". The EMBO Journal 16 (18): 5672–86. doi:10.1093/emboj/16.18.5672. PMC 1170199. PMID 9312026. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.