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Protein ZBTB17 PDB 2Q81.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67, zinc finger and BTB domain containing 17
External IDs MGI: 107410 HomoloGene: 2575 GeneCards: ZBTB17
Genetically Related Diseases
dilated cardiomyopathy[1]
RNA expression pattern
PBB GE ZBTB17 203601 s at tn.png

PBB GE ZBTB17 203602 s at tn.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC) Chr 1: 15.94 – 15.98 Mb Chr 4: 141.44 – 141.47 Mb
PubMed search [2] [3]
View/Edit Human View/Edit Mouse

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.[4]


ZBTB17 has been shown to interact with TOPBP1,[5] Host cell factor C1[6] and Myc.[7][8]


  1. ^ "Diseases that are genetically associated with ZBTB17 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ "Entrez Gene: ZBTB17 zinc finger and BTB domain containing 17". 
  5. ^ Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, Syvaoja J, Saluz HP, Haenel F, Eilers M (Sep 2002). "Negative regulation of the mammalian UV response by Myc through association with Miz-1". Molecular Cell. 10 (3): 509–21. doi:10.1016/S1097-2765(02)00633-0. PMID 12408820. 
  6. ^ Piluso D, Bilan P, Capone JP (Nov 2002). "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of Biological Chemistry. 277 (48): 46799–808. doi:10.1074/jbc.M206226200. PMID 12244100. 
  7. ^ Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M (Apr 2001). "Repression of p15INK4b expression by Myc through association with Miz-1". Nature Cell Biology. 3 (4): 392–9. doi:10.1038/35070076. PMID 11283613. 
  8. ^ Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M (Sep 1997). "An alternative pathway for gene regulation by Myc". The EMBO Journal. 16 (18): 5672–86. doi:10.1093/emboj/16.18.5672. PMC 1170199Freely accessible. PMID 9312026. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.