ZNF238

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ZBTB18
Identifiers
AliasesZBTB18, C2H2-171, MRD22, RP58, TAZ-1, ZNF238, zinc finger and BTB domain containing 18
External IDsMGI: 1353609 HomoloGene: 21276 GeneCards: ZBTB18
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for ZBTB18
Genomic location for ZBTB18
Band1q44Start244,048,939 bp[1]
End244,057,476 bp[1]
RNA expression pattern
PBB GE ZNF238 207164 s at fs.png

PBB GE ZNF238 212774 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278196
NM_006352
NM_205768

RefSeq (protein)

NP_001265125
NP_006343
NP_991331

Location (UCSC)Chr 1: 244.05 – 244.06 MbChr 1: 177.44 – 177.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 238 is a protein that in humans is encoded by the ZNF238 gene.[5][6][7]

Function[edit]

C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly.[supplied by OMIM][7]

Interactions[edit]

ZNF238 has been shown to interact with DNMT3A.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000179456 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063659 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Becker KG, Lee IJ, Nagle JW, Canning RD, Gado AM, Torres R, Polymeropoulos MH, Massa PT, Biddison WE, Drew PD (November 1997). "C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain". International Journal of Developmental Neuroscience. 15 (7): 891–9. doi:10.1016/S0736-5748(97)00034-8. PMID 9568537.
  6. ^ Aoki K, Ishida R, Kasai M (January 1997). "Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX". FEBS Letters. 401 (2–3): 109–12. doi:10.1016/S0014-5793(96)01444-5. PMID 9013868.
  7. ^ a b "Entrez Gene: ZNF238 zinc finger protein 238".
  8. ^ Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T (May 2001). "Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription". The EMBO Journal. 20 (10): 2536–44. doi:10.1093/emboj/20.10.2536. PMC 125250. PMID 11350943.

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.