From Wikipedia, the free encyclopedia
Jump to: navigation, search
Zinc finger and BTB domain containing 18
Symbols ZBTB18 ; C2H2-171; MRD22; RP58; TAZ-1; ZNF238
External IDs OMIM608433 MGI1353609 HomoloGene21276 GeneCards: ZBTB18 Gene
RNA expression pattern
PBB GE ZNF238 212774 at tn.png
PBB GE ZNF238 207164 s at tn.png
More reference expression data
Species Human Mouse
Entrez 10472 30928
Ensembl ENSG00000179456 ENSMUSG00000063659
UniProt Q99592 Q9WUK6
RefSeq (mRNA) NM_001278196 NM_001012330
RefSeq (protein) NP_001265125 NP_001012330
Location (UCSC) Chr 1:
244.05 – 244.06 Mb
Chr 1:
177.44 – 177.45 Mb
PubMed search [1] [2]

Zinc finger protein 238 is a protein that in humans is encoded by the ZNF238 gene.[1][2][3]

C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly.[supplied by OMIM][3]


ZNF238 has been shown to interact with DNMT3A.[4]


  1. ^ Becker KG, Lee IJ, Nagle JW, Canning RD, Gado AM, Torres R, Polymeropoulos MH, Massa PT, Biddison WE, Drew PD (June 1998). "C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain". Int J Dev Neurosci 15 (7): 891–9. doi:10.1016/S0736-5748(97)00034-8. PMID 9568537. 
  2. ^ Aoki K, Ishida R, Kasai M (February 1997). "Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX". FEBS Lett 401 (2-3): 109–12. doi:10.1016/S0014-5793(96)01444-5. PMID 9013868. 
  3. ^ a b "Entrez Gene: ZNF238 zinc finger protein 238". 
  4. ^ Fuks, F; Burgers W A; Godin N; Kasai M; Kouzarides T (May 2001). "Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription". EMBO J. (England) 20 (10): 2536–44. doi:10.1093/emboj/20.10.2536. ISSN 0261-4189. PMC 125250. PMID 11350943. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.