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Zinc finger protein 239
Symbols ZNF239 ; HOK-2; MOK2
External IDs OMIM601069 MGI1306812 HomoloGene68480 GeneCards: ZNF239 Gene
RNA expression pattern
PBB GE ZNF239 206261 at tn.png
More reference expression data
Species Human Mouse
Entrez 8187 22685
Ensembl ENSG00000196793 ENSMUSG00000042097
UniProt Q16600 P24399
RefSeq (mRNA) NM_001099282 NM_001001792
RefSeq (protein) NP_001092752 NP_001001792
Location (UCSC) Chr 10:
43.56 – 43.57 Mb
Chr 6:
117.86 – 117.87 Mb
PubMed search [1] [2]

Zinc finger protein 239 is a protein that in humans is encoded by the ZNF239 gene.[1][2][3]


MOK2 proteins are DNA- and RNA-binding proteins that are mainly associated with nuclear RNP components, including the nucleoli and extranucleolar structures.[3][4]


ZNF239 has been shown to interact with LMNA.[5]


  1. ^ Arranz V, Kress M, Ernoult-Lange M (Jan 1996). "Localization of zinc finger Mok2 gene to mouse chromosome 6, a new region of homology with human chromosome 19". Mammalian Genome 7 (1): 77–8. doi:10.1007/s003359900020. PMID 8903737. 
  2. ^ Ernoult-Lange M, Arranz V, Le Coniat M, Berger R, Kress M (Dec 1995). "Human and mouse Krüppel-like (MOK2) orthologue genes encode two different zinc finger proteins". Journal of Molecular Evolution 41 (6): 784–94. doi:10.1007/bf00173158. PMID 8587123. 
  3. ^ a b "Entrez Gene: ZNF239 zinc finger protein 239". 
  4. ^ Arranz V, Harper F, Florentin Y, Puvion E, Kress M, Ernoult-Lange M (Apr 1997). "Human and mouse MOK2 proteins are associated with nuclear ribonucleoprotein components and bind specifically to RNA and DNA through their zinc finger domains". Molecular and Cellular Biology 17 (4): 2116–26. PMC 232059. PMID 9121460. 
  5. ^ Dreuillet C, Tillit J, Kress M, Ernoult-Lange M (Nov 2002). "In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C". Nucleic Acids Research 30 (21): 4634–42. doi:10.1093/nar/gkf587. PMC 135794. PMID 12409453. 

Further reading[edit]

\* Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. 

  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.