ZNF638

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ZNF638
Identifiers
AliasesZNF638, NP220, ZFML, Zfp638, zinc finger protein 638
External IDsMGI: 1203484 HomoloGene: 7447 GeneCards: ZNF638
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for ZNF638
Genomic location for ZNF638
Band2p13.3-p13.2Start71,276,561 bp[1]
End71,435,069 bp[1]
RNA expression pattern
PBB GE ZNF638 211257 x at fs.png

PBB GE ZNF638 213775 x at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001014972
NM_001252612
NM_001252613
NM_014497

NM_001166371
NM_008717
NM_001355284
NM_001355285
NM_001355286

RefSeq (protein)

NP_001014972
NP_001239541
NP_001239542
NP_055312

NP_001159843
NP_032743
NP_001342213
NP_001342214
NP_001342215

Location (UCSC)Chr 2: 71.28 – 71.44 MbChr 6: 83.87 – 83.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.[5][6]

The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.[6]

Interactions[edit]

ZNF638 has been shown to interact with FHL2.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000075292 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030016 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Inagaki H, Matsushima Y, Nakamura K, Ohshima M, Kadowaki T, Kitagawa Y (Jul 1996). "A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain". J Biol Chem. 271 (21): 12525–31. doi:10.1074/jbc.271.21.12525. PMID 8647861.
  6. ^ a b "Entrez Gene: ZNF638 zinc finger protein 638".
  7. ^ Ng, Enders Kai On; Chan Kwok Keung; Wong Chi Hang; Tsui Stephen Kwok Wing; Ngai Sai Ming; Lee Simon Ming Yuen; Kotaka Masayo; Lee Cheuk Yu; Waye Mary Miu Yee; Fung Kwok Pui (2002). "Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220". J. Cell. Biochem. United States. 84 (3): 556–66. doi:10.1002/jcb.10041. ISSN 0730-2312. PMID 11813260.

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.