Whyte studied at Wilberforce University, where he played banjo with Horace Henderson and arranged pieces for him. He led his own Cincinnati-based bands from the early 1920s, and put together the Chocolate Beau Brummels late in the decade. This ensemble recorded for Gennett, Supertone, and Champion in 1929, amounting to about ten tunes. Some of the recordings were released under the names "Eddie Walker & His Band" and "Smoke Jackson & His Red Onions". Among those who played in Whyte's bands were Herman Chittison, Jerry Blake, Truck Parham, Sy Oliver, Roy Eldridge, Vic Dickenson, and Al Sears.
Whyte's entire discography was reissued to CD on a Jazz Oracle compilation, Richmond Rarities 1927-31.