Zapotin

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Zapotin
Zapotin.svg
Names
IUPAC name
2-(2,6-Dimethoxyphenyl)-5,6-dimethoxy-4H-chromen-4-one
Identifiers
3D model (JSmol)
ChemSpider
Properties
C19H18O6
Molar mass 342.35 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Zapotin is a natural chemical compound, classified as a flavone, isolated from White sapote (Casimiroa edulis).[1]

Several recent in vitro studies have shown that zapotin has potential anti-carcinogenic effects against isolated colon cancer cells.[2][3]

References[edit]

  1. ^ Sondheimer, F (1960). "Constituents of Casimiroa edulis Llave et Lex.—VI 2′,5,6-Trimethoxyflavone, 2′,5,6,7-tetramethoxyflavone (zapotin) and 5-hydroxy-2′,6,7-trimethoxyflavone (zapotinin)". Tetrahedron. 9 (3–4): 139–144. doi:10.1016/0040-4020(60)80001-4. 
  2. ^ Murillo G, Hirschelman WH, Ito A, et al. (2007). "Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis". Nutrition and Cancer. 57 (1): 28–37. doi:10.1080/01635580701268097. PMID 17516860. 
  3. ^ Maiti A, Cuendet M, Kondratyuk T, Croy VL, Pezzuto JM, Cushman M (Jan 2007). "Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis". Journal of Medicinal Chemistry. American Chemical Society. 50 (2): 350–5. doi:10.1021/jm060915+. PMC 2523270Freely accessible. PMID 17228877.